Designed shortly after the College was founded in 1854, the seal features an outer circle containing the words Columbia College and the motto Non Quem Sed Quid (not who, but what). In the inner circle is a scroll upon which are pictured the lamp of learning, representing the spirit of wisdom and constant renewal, and an open book representing knowledge and the quest for truth. Beneath the scroll is the date of the founding of the College.

The College unveiled its mace at commencement ceremonies in 1985. The shaft is dark walnut incised with a swirling pattern. The finial, nodule and head are solid brass electroplated in 24-carat gold. The head is embellished with four circular plaques mounted on projecting cylinders and engraved with the College's previous "lamp of learning" logo; the emblem of the United Methodist Church; the South Carolina state seal; and the inscription, "Presented to Columbia College in honor of Ralph Thomas Mirse, President, May 4, 1985." Atop the three-foot mace is a representation of the College Seal.

The mace was designed by President Mirse, executive assistant Peggy Reeves, and Edward Rapopo